The Responsible Sexual Behavior Initiative, funded by the AIDS Funding Collaborative, provides comprehensive sexuality education to students in grades K -12 in the Cleveland Metropolitan School District. Evaluation of this initiative involves analysis of changes in student knowledge, attitude, and behavioral intent, as well as changes in District policies vis-à-vis sexuality education. Students in each of the selected schools are surveyed using a pre-test/post-test design. Local stakeholders, as well as teachers and principals are interviewed about the curriculum, and parents are asked to complete surveys regarding their thoughts about comprehensive sex education. In addition, a field team from Philliber conducts classroom observations to measure fidelity to the four curricula used in the initiative. Using this design, Philliber is able to provide information about the impact of the curricula on CMSD students, the response to the curricula by local stakeholders, and the extent to which the schools and teachers maintain fidelity to the implementation plan.